Abstract

In this paper we introduce a novel and efficient approach to detect topics in a large corpus of research papers. With rapidly growing size of academic literature, the problem of topic detection has become a very challenging task. We present a unique approach that uses closed frequent keyword-set to form topics. Our approach also provides a natural method to cluster the research papers into hierarchical, overlapping clusters using topic as similarity measure. To rank the research papers in the topic cluster, we devise a modified PageRank algorithm that assigns an authoritative score to each research paper by considering the sub-graph in which the research paper appears. We test our algorithms on the DBLP dataset and experimentally show that our algorithms are fast, effective and scalable.

Abstract

In this paper we introduce a novel and efficient approach to detect and rank topics in a large corpus of research papers. With rapidly growing size of academic literature, the problem of topic detection and topic ranking has become a challenging task. We present a unique approach that uses closed frequent keyword-set to form topics. We devise a modified time independent Page Rank algorithm that assigns an authoritative score to each topic by considering the sub-graph in which the topic appears, producing a ranked list of topics.The use of citation network and the introduction of time in variance in the topic ranking algorithm reveal very interesting results. Our approach also provides a clustering technique for the research papers using topics as similarity measure. We extend our algorithms to study various aspects of topic evolution which gives interesting insight into trends in research areas over time.Our algorithms also detect hot topics and landmark topics over the years. We test our algorithms on the DBLP dataset and show that our algorithms are fast, effective and scalable.

Abstract

Measuring inter-document similarity is one of the most essential steps in text document clustering. Traditional methods rely on representing text documents using the simple Bag-of-Words (BOW) model which assumes that terms of a text document are independent of each other. Such single term analysis of the text completely ignores the underlying (semantic) structure of a document. In the literature, sufficient efforts have been made to enrich BOW representation using phrases and n-grams like bi-grams and tri-grams. These approaches take into account dependency only between adjacent terms or a continuous sequence of terms. However, while some of the dependencies exist between adjacent words, others are more distant. In this paper, we make an effort to enrich traditional document vector by adding the notion of term-pair features. A Term-Pair feature is a pair of two terms of the same document such that they may be adjacent to each other or distant. We investigate the process of term-pair selection and propose a methodology to select potential term-pairs fromthe given document. Utilizing term proximity between distant terms also allows some flexibility for two documents to be similar if they are about similar topics but with varied writing styles. Experimental results on standard web document data set show that the clustering performance is substantially improved by adding term-pair features.

Abstract

In this paper we analyze the topological properties of airport network of India (ANI) using graph theoretic approach. We show that such an analysis can be useful not only in planning the infrastructure and growth of the air-traffic connectivity, but also in managing the flow of transportation during emergencies such as accidental failure of the airport, close down of the airport due to unexpected climate changes, terrorist attacks, etc. Knowledge of the connectivity pattern and load on various routes can also help in making judicious decisions for reduction of flights to contain the spread of the infectious disease.

Abstract

The recent large scale advances in science and technology has resulted in accumulation of large amount of biological pathways data. Any metabolic pathway contains large number of enzymes, metabolites and reactions. To make sense of diverse data available on a system, one needs to correlate and analyze them as a whole. Motivated by the potential benefits of graph theory and its application in biological data, we discuss the automated reconstruction and analysis of metabolite network of Arabidopsis thaliana using concepts of graph theory. A.thaliana metabolite network was reconstructed and analysis of the global properties of its metabolite-centric graph shows that the network is small-world and scale-free in nature. The investigation of nodes with high centrality values like high degree and high betweeness in this network help in identifying important metabolites, reactions, etc. Newman’s modularity-based approach has been used in the analysis of the metabolite network of A. thaliana to identify pathway clusters, isolated pathways, and orphan metabolites or products. Our analysis on network representations helps in understanding the relationship between the metabolites, enzymes and reactions of metabolic pathways in A. thaliana.

Abstract

Graph comparisons, quantitative characterizations, computation of topological indices, clustering and partitioning are some of the major computations of graph that have yielded valuable results in various disciplines. Motivated by the potential benefits of graph theory application on biological data, we discuss the reconstruction and analysis of enzyme centric network of Arabidopsis thaliana using graph theory concepts. We had earlier constructed the metabolite network of Arabidopsis thaliana and witnessed the scale free and small world nature of the network. Compared to metabolites, the enzymes are more conserved in and across many pathways. So the aim of constructing the enzyme centric network is to see if the network follows similar network properties of the metabolite network and to look for additional details that a metabolite network cannot reveal. The enzyme flat file from KEGG FTP is used as the data set for the reconstruction of the enzyme centric network. We examined the network to find the relationship between topological connections among enzymes and their functions during evolution. The enzyme sequences of high degree and high betweenness enzymes belonged to ancient fold class and ancestry value showing evidence that they evolved very slowly.

Abstract

IGIPT is a web-based integrated platform for the identification of genomic islands (GIs). It incorporates thirteen parametric measures based on anomalous nucleotide composition on a single platform, thus improving the predictive power of a horizontally acquired region, since it is known that no single measure can absolutely predict a horizontally transferred region. The tool filters putative GIs based on standard deviation from genomic average and also provide raw output in MS excel format for further analysis. To facilitate the identification of various structural features, viz., tRNA integration sites, repeats, etc. in the vicinity of GIs, the tool provides option to extract the predicted regions and its flanking regions.

Abstract

Pattern discovery is at the heart of bioinformatics, and algorithms from computer science have been widely used for identifying biological patterns. The assumption behind pattern discovery approaches is that a pattern that occurs often enough in biological sequences/structures or is conserved across organisms is expected to play a role in defining the respective sequence’s or structure’s functional behavior and/or evolutionary relationships. The pattern recognition problem addressed here is at the genomic level and involves identifying horizontally transferred regions, called genomic islands. A horizontally transferred event is defined as the movement of genetic material between phylogenetically unrelated organisms by mechanisms other than parent to progeny inheritance. Increasing evidence suggests the importance of horizontal transfer events in the evolution of bacteria, influencing traits such as antibiotic resistance, symbiosis and fitness, virulence, and adaptation in general. In the genomic era, with the availability of large number of bacterial genomes, the identification of genomic islands also form the first step in the annotation of the newly sequenced genomes and in identifying the differences between virulent and non-virulent strains of a species. Considerable effort is being made in their identification and analysis and in this chapter a brief summary of various approaches used in the identification and validation of horizontally acquired regions is discussed.

Abstract

We study the problem of secure message transmission (SMT) in asynchronous directed graphs, where an unbounded Byzantine adversary can corrupt some subset of nodes specified via an adversary structure. We focus on the particular variant (0, δ)-SMT, where the message remains perfectly private, but there is a small chance that the receiver R may not obtain it. This variant can be of two kinds: Monte Carlo - where R may output an incorrect message with small probability; and Las Vegas - where R never outputs an incorrect message. For a Monte Carlo (0, δ)-SMT protocol to exist in an asynchronous directed graph, we show that the minimum connectivity required in the network does not decrease even when privacy of the message being transmitted is not required. In the case of Las Vegas (0, δ)-SMT, we show that the minimum connectivity required matches exactly with the minimum connectivity requirements of the zero-error variant of SMT – (0, 0)-SMT. For a network that meets the minimum connectivity requirements, we provide a protocol efficient in the size of the graph and the adversary structure. We also provide a protocol efficient in the size of the graph for an important family of graphs, when the adversary structure is threshold.

Abstract

In this paper, we give approximate algorithms for privacy preserving distance based outlier detection for both horizontal and vertical distributions, which scale well to large datasets of high dimensionality in comparison with the existing techniques. In order to achieve efficient private algorithms, we introduce an approximate outlier detection scheme for the centralized setting which is based on the idea of Locality Sensitive Hashing. We also give theoretical and empirical bounds on the level of approximation of the proposed algorithms.